U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07916805) titled 'Effects of Expectancy and Mindfulness Instructions on Chronic Pain' on Oct. 29.
Brief Summary: This randomized 2x2 factorial study will examine how verbal expectancy framing and mindfulness-specific practice instructions influence acute pain and brain activity in adults with chronic pain. Sixty meditation-naive adults will be assigned to one of four conditions combining positive or negative expectancy framing with either a guided mindfulness exercise or a sham-meditation comparison exercise. Pain intensity, pain unpleasantness, anxiety, desire for pain medication, and mindfulness-related psychological states will be assessed before a...