Clinical Trial: Effectiveness and Safety of Penehyclidine Hydrochloride for Improving Microcirculatory Dysfunction in Critically Ill Children

U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07519226) titled 'Effectiveness and Safety of Penehyclidine Hydrochloride for Improving Microcirculatory Dysfunction in Critically Ill Children' on April 02.

Brief Summary: This prospective randomized controlled trial was designed to evaluate whether the M1/M3-selective antagonist penehyclidine hydrochloride could more effectively reverse pediatric microcirculatory dysfunction than traditional atropine, particularly when macrohemodynamics appear normalized.

Study Start Date: May 08, 2024

Study Type: INTERVENTIONAL

Condition: Shock

Intervention: DRUG: atropine control group

atropine control group

DRUG: penehyclidine hydrochloride group

peneh...