Clinical Trial: Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands

U.S., Aug. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07753811) titled 'Effect of Oral Isotretinoin on Ocular Surface and Meibomian Glands' on Aug. 01.

Brief Summary: The aim of the study was to evaluate meibomian gland morphology using non-contact meibography and ocular surface changes in patients with acne vulgaris treated with isotretinoin as indicators of dry eye, which is known to be a side effect of isotretinoin.

Study Start Date: Jan. 01, 2024

Study Type: INTERVENTIONAL

Condition: Dry Eye Disease (DED) Meibomian Gland Dysfunction (Disorder) Acne Vulgaris

Intervention: DRUG: isotretinoin

1. Meibomian Gland Morphology (Meiboscore)

2. Ocular Surface Disease Index (OSDI) Score

3. Invasive Te...