U.S., Nov. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07912567) titled 'Effect of Midazolam Given at Induction on Recall of Propofol Injection Pain' on Oct. 12.
Brief Summary: Propofol is the most commonly used intravenous drug to start general anesthesia (induction). However, it often causes pain in the arm during injection, and remembering this pain after surgery can negatively affect the patient's experience and comfort. Adding lidocaine (a local anesthetic) to propofol reduces this pain but does not prevent it in every patient. Midazolam is a medicine commonly given to reduce anxiety, and it can also reduce the memory of events that occur after it is given (anterograde amnesia). It is not known wheth...