Clinical Trial: Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp.

U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07495605) titled 'Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp.' on March 08.

Brief Summary: To compare the effect of 1% melatonin gel versus calcium hydroxide as intra canal medication in necrotic mandibular premolars on:

* Intensity of postoperative pain.

* Bacterial load reduction.

* Periapical (MMP-9) level.

Study Start Date: March 22

Study Type: INTERVENTIONAL

Condition: Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic ...