U.S., July 10 -- ClinicalTrials.gov registry received information related to the study (NCT07691892) titled 'Early Warning and Risk Prediction of Medication-Related Osteonecrosis of the Jaw' on July 02.

Brief Summary: This prospective observational cohort study aims to develop and evaluate an early warning and risk prediction model for medication-related osteonecrosis of the jaw (MRONJ) based on multimodal data fusion.

Eligible participants will include adults who have received bone-modifying agents, including bisphosphonates or denosumab, for at least 24 months for osteoporosis or bone metastases and who are scheduled to undergo clinically indicated invasive oral procedures. The study will not assign any treatment or intervention. All or...