U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT07508514) titled 'Early Temporal Dynamics of Optic Nerve Sheath Diameter After Therapy in GCA' on March 23.
Brief Summary: Giant cell arteritis (GCA) is an inflammatory disease of large and medium arteries that can cause irreversible vision loss. Glucocorticoids (GCs) rapidly suppress inflammation, but diagnostic imaging tests such as temporal artery ultrasound or biopsy often become falsely negative within days of treatment. The optic nerve sheath diameter (ONSD), measurable by ocular ultrasound, reflects perineural edema and may serve as a quantitative biomarker of ocular inflammation in GCA.
The SONIC-TIME study (Early Temporal Dynamics of Optic ...