U.S., Oct. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07879924) titled 'Dual Neuromodulation for Depression: Boosting TMS With tES' on Aug. 24.
Brief Summary: Major depressive disorder (MDD) is a common and disabling condition. Transcranial magnetic stimulation (TMS) is an established non-invasive neuromodulation treatment for depression, but clinical response varies considerably between individuals. One possible reason for this variability is that the effects of TMS may depend on the pattern of ongoing brain activity at the time stimulation is delivered.
This mechanistic, randomised, single-blind study will investigate whether synchronising TMS with transcranial alternating current stimulation (tACS),...