U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT07550621) titled 'Drug-Drug Interaction Study of MDR-001 With Rifampin and Itraconazole in Healthy Adult Participants' on April 11.
Brief Summary: A Phase I, open-label, fixed-sequence, two-part drug-drug interaction study in healthy Chinese adults to evaluate the effect of multiple-dose rifampin (Part A) or itraconazole (Part B) on the single-dose pharmacokinetics of MDR-001, an oral GLP-1 receptor agonist.
Study Start Date: May 06
Study Type: INTERVENTIONAL
Condition:
Healthy Volunteers (HV)
Intervention:
DRUG: MDR-001
Oral small-molecule GLP-1 receptor agonist ;Investigational drug (not yet approved)
DRUG: Rifampin
Strong CYP3A4 inducer;...