Clinical Trial: Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases

U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT07444606) titled 'Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases' on Feb. 26.

Brief Summary: The goal of this clinical research study is to find the recommended dose level and recommended number of injections of the study agent DNX-2401 that can be given to patients with metastatic melanoma that have intracranial and/or extracranial lesions.

Study Start Date: Aug. 31, 2026

Study Type: INTERVENTIONAL

Condition: Melanoma

Intervention: DRUG: DNX-2401

Given by injection

Recruitment Status: NOT_YET_RECRUITING

Sponsor: M.D. Anderson Cancer Center

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