U.S., March 26 -- ClinicalTrials.gov registry received information related to the study (NCT07493785) titled 'Dexmedetomidine for Invasive Ventilation In the NEOnate' on Feb. 23.
Brief Summary: Despite the increasing use of non-invasive ventilation, a large majority of premature neonates still receive invasive ventilation during their NICU (neonatal intensive care unit) stay. Invasive ventilation is a unanimous source of discomfort and pain.
As opposed to the adult and pediatric population, routine use of opioids or midazolam is not recommended in ventilated neonates.
Although opioids are the most frequently prescribed analgosedative drugs in ventilated premature neonates, their use is controversial because of the risk of respiratory dep...