Clinical Trial: Development and Validation of a Circulating Tumour DNA Marker for Pre-neoplastic Colorectal Tumours.

U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07776548) titled 'Development and Validation of a Circulating Tumour DNA Marker for Pre-neoplastic Colorectal Tumours.' on July 30.

Brief Summary: The goal of this prospective interventional biomarker development and validation study is to determine whether circulating tumour DNA (ctDNA) can be detected in patients with large pre-neoplastic colorectal lesions undergoing endoscopic resection and whether ctDNA can be used to identify local recurrence after resection.

The main questions it aims to answer are:

* Can advanced colorectal laterally spreading tumours (LSTs) shed detectable ctDNA into the bloodstream before endoscopic resection?

* Can ctDN...