U.S., Oct. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07900737) titled 'Comparison of Two Timings of Levothyroxine Intake in Hypothyroid Patients: A Cross-over Randomized Control Trial' on Sept. 17, 2025.
Brief Summary: Primary hypothyroidism is a common condition, affecting nearly 10% of the general population. Its treatment is levothyroxine, a synthetic thyroid hormone with a half-life of nearly eight days. Optimal absorption of levothyroxine occurs when it is taken on an empty stomach. It is generally recommended to take the medication in the morning, at least 30 minutes before breakfast. However, this treatment regimen can be challenging for some patients. Missed doses constitute a problem, leading ...