U.S., Jan. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07357233) titled 'Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides' on Dec. 20, 2025.
Brief Summary: General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique.
Specific aim: correlation between post operative pain and release of Substance P and Calcitonin gene-related peptide.
Study Start Date: Sept. 01, 2025
Study Type: INTERVENTIONAL
Condition:
Post Operative Pain
Intervention:
OTHER: Manual-less
Canals preparation with rotary dota files escaping scouting and glide path step
OTHER: Conventional technique
Ca...