U.S., Jan. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07378761) titled 'Comparing UDCA and Corticosteroids in Immunotherapy Induced Cholestatic Hepatitis' on Jan. 22.
Brief Summary: The clinical trial aims to compare the effectiveness of ursodeoxycholic acid (UDCA) to corticosteroids in treating cholestatic hepatitis induced by immune checkpoint inhibitors (ICIs) over a 21-day period.
The trial presents a detailed scientific justification for comparing UDCA to corticosteroids, describing the treatment and detailing the follow-up procedures. It hypothesizes that UDCA could be superior to corticosteroids for treating ICI-related cholestatic hepatitis, based on its established use in primary biliary chola...