U.S., Jan. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07378137) titled 'Comparing the Components of Composite Endpoints for Healthcare Providers and Patients' on Jan. 22.
Brief Summary: Clinical trials often employ a composite primary endpoint to increase event rates and enhance trial efficiency. However, analytic approaches to composite endpoints typically assume that the individual components are of similar importance. In practice, a treatment often has different effects on each individual endpoint, leading to uncertainty in interpreting the results of a clinical trial employing a composite primary endpoint.
Some investigators have recommended using a weighted composite endpoint to address these conc...