U.S., Nov. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07919275) titled 'Comparing Long-Acting Local Pain Relief Methods in PLIF Surgery' on Nov. 01.
Brief Summary: This study is being done to compare three ways of using long-acting local pain medicine around the surgical wound during open lumbar fusion surgery. The goal is to learn which approach gives better pain relief after surgery, reduces the need for additional pain medicine such as tramadol, and causes fewer side effects such as nausea, vomiting, constipation, or wound problems. Participants will be adults aged 18 to under 75 years who are scheduled for open posterior lumbar fusion for degenerative lumbar disease and who agree to take part. They w...