Clinical Trial: Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma

U.S., March 21 -- ClinicalTrials.gov registry received information related to the study (NCT07485777) titled 'Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma' on March 17.

Brief Summary: It's a prospective, randomised, assessor-blinded clinical study comparing topical 30% metformin with Kligman's regimen for melasma in women aged 35-55 years at Fauji Foundation Hospital, Rawalpindi. The study seeks to ascertain which treatment yields a more significant decrease in the modified MASI score over an 8-week period and which treatment is associated with fewer adverse effects, such as erythema, burning, peeling, and post-inflammatory hyperpigmentation. A total of 82 participants will be enrolled and ran...