U.S., July 29 -- ClinicalTrials.gov registry received information related to the study (NCT07730814) titled 'Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media)' on July 23.
Brief Summary: This study is being conducted at multiple hospitals and clinics to better understand whether antibiotics truly help children feel better when they have an ear infection (acute otitis media). Children in the study are randomly assigned (like flipping a coin) to receive either amoxicillin, amoxicillin-clavulanate, or a placebo (a look-alike medicine with no active antibiotic). Neither families nor study staff know which treatment the child is receiving during the study. The main goal is to compare...