U.S., May 12 -- ClinicalTrials.gov registry received information related to the study (NCT07577661) titled 'Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea' on April 27.
Brief Summary: Obstructive sleep apnea (OSA) is a common condition in which the airway repeatedly collapses during sleep, leading to poor sleep quality and reduced oxygen levels. Hypoglossal nerve stimulation (HGNS) is an approved treatment that uses a small implanted device to stimulate the genioglossus muscle and keep the airway open. However, some patients continue to have OSA despite using HGNS. Atomoxetine and oxybutynin, "AtoOxy", is a promising pharmacologcal therapy under investigation that has been shown to activate ...