U.S., Dec. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07297069) titled 'Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO Trial' on Dec. 09.
Brief Summary: In adults hospitalized with acute severe ulcerative colitis who fail to respond to intravenous steroids, does treatment with a combination of infliximab and tofacitinib, compared with infliximab alone or tofacitinib alone, result in higher rates of early clinical remission and mucosal healing, and fewer treatment-related complications over a 10 week period
Study Start Date: Jan. 01, 2026
Study Type: INTERVENTIONAL
Condition:
Acute Severe Ulcerative Colitis
Intervention:
DRUG: Infliximab
Participant...