U.S., Jan. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07350252) titled 'Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty' on Dec. 22, 2025.
Brief Summary: The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral cutaneous nerve (AFCN) block in participants undergoing total knee arthroplasty (TKA). The primary outcome is pain intensity, measured using the Numerical Rating Scale (NRS) at multiple time points after surgery. Secondary outcomes include opioid consumption, time to mobilization, postoperative na...