U.S., March 28 -- ClinicalTrials.gov registry received information related to the study (NCT07498244) titled 'Collagen Fingerprinting for Stratification of PH Patients' on March 23.
Brief Summary: Chronic lung diseases like pulmonary fibrosis and COPD (Chronic Obstructive Pulmonary Disease) can lead to pulmonary hypertension, a serious complication where increased pressure in lung vessels strains the heart and worsens outcomes. Because early symptoms are unclear, diagnosis often comes too late, highlighting the need for simple, non-invasive early detection methods.
A key driver of the disease is vascular remodeling, where blood vessels narrow and stiffen. This involves changes in the extracellular matrix, particularly the understudied bas...