U.S., Jan. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07355400) titled 'Clinical Evaluation of the NeoPill Device for Reduction of Oral Bacterial Load in Patients With Fixed Orthodontic Appliances' on Dec. 16, 2025.

Brief Summary: This study evaluates the effectiveness of the NeoPill oral hygiene device in reducing oral bacterial load in adults wearing fixed orthodontic appliances. Maintaining oral hygiene is challenging for orthodontic patients due to limited access around brackets and wires, and current solutions often rely on chemical-based products and disposable tools.

NeoPill is a reusable, battery-operated oral device designed to provide mechanical cleansing of the oral cavity. In this single-ar...