Clinical Trial: Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne

U.S., Oct. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07881315) titled 'Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne' on Oct. 12.

Brief Summary: This randomised trial compares two treatments added to the same standard acne gel in people with moderate facial acne. All participants will use adapalene 0.1%/benzoyl peroxide 2.5% gel at night. Half will also use clascoterone 1% cream (a non-antibiotic cream that blocks the effect of androgen hormones in the skin), and half will use clindamycin 1% lotion (a topical antibiotic), twice daily for 12 weeks. The main question is whether the reduction in inflamed acne spots (papules and pustules) after 12 weeks differ...