Clinical Trial: Circulating Muscle-specific microRNAs and Renal, Nutritional and Inflammatory Biomarkers of Skeletal Muscle Loss During the First 18 Months After Laparoscopic Sleeve Gastrectomy

U.S., Sept. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07806513) titled 'Circulating Muscle-specific microRNAs and Renal, Nutritional and Inflammatory Biomarkers of Skeletal Muscle Loss During the First 18 Months After Laparoscopic Sleeve Gastrectomy' on Sept. 01.

Brief Summary: Metabolic and bariatric surgery produces substantial and durable weight loss, but a considerable proportion of that loss is not adipose tissue. Pooled estimates indicate approximately 8 kg of fat-free mass and 3 kg of skeletal muscle mass are lost within twelve months, with more than half occurring in the first three months. No validated circulating biomarker of skeletal muscle loss exists for this population, and body compositio...