U.S., July 9 -- ClinicalTrials.gov registry received information related to the study (NCT07689435) titled 'Cholesterol Cream vs Urea Cream for Skin Barrier and Quality of Life in Ichthyosis' on June 30.
Brief Summary: This study looks at whether a cream containing 10% cholesterol works better than a cream containing 10% urea for people with autosomal recessive congenital ichthyosis (ARCI), a rare inherited skin condition that causes dry, thickened, scaly skin from birth.
People with ARCI have a weakened skin barrier because their skin cannot properly produce or arrange the natural fats (lipids) needed to keep moisture in and irritants out. This leads to excessive water loss through the skin, dryness, itching, cracking, and a higher risk ...