U.S., April 21 -- ClinicalTrials.gov registry received information related to the study (NCT07538089) titled 'Caries Removal Methods and Microbiome Changes' on April 12.
Brief Summary: Dental caries management approaches may influence not only tissue removal but also the microbial composition within the cavity. However, clinical evidence on how different caries removal methods affect the oral microbiome remains limited.
This study aims to evaluate the effects of selective and non-selective caries removal methods on the diversity and composition of the oral microbiome using 16S rRNA gene sequencing. The findings are expected to help identify biologically compatible treatment approaches that effectively reduce pathogenic microorganisms.
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