U.S., March 5 -- ClinicalTrials.gov registry received information related to the study (NCT07450287) titled 'CardioNETPOL National Registry of Carcinoid Heart Disease' on Feb. 19.

Brief Summary: Carcinoid tumors are neuroendocrine tumors (NETs), most commonly originating from the gastrointestinal tract, that may secrete bioactive substances such as serotonin. Persistent exposure to these mediators can lead to carcinoid syndrome and, in up to 50% of patients, carcinoid heart disease (CHD). CHD is characterized by fibrotic degeneration of cardiac valves, predominantly right-sided, resulting in progressive valvular dysfunction and a significant increase in mortality.

The mechanisms underlying selective cardiac involvement and predictors of d...