U.S., Jan. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07350837) titled 'CAR-T Therapy Targeting CD19 and BCMA in Highly Sensitized Kidney Transplant Participants' on Dec. 29, 2025.
Brief Summary: The purpose of this study is to assess the safety, tolerability, and efficacy of AZD0120 in highly sensitized adult participants with ESKD awaiting kidney transplant-who, as assessed by investigators, are improbable desensitization through conventional treatments (e.g., plasmapheresis and immunoadsorption)- with or without living donors.
Study Start Date: Dec. 31, 2025
Study Type: INTERVENTIONAL
Condition:
Highly Sensitized Patients Awaiting Kidney Transplant
Intervention:
DRUG: AZD0120
Treatment duratio...