U.S., July 11 -- ClinicalTrials.gov registry received information related to the study (NCT07696845) titled 'C-PRF With Minimally Invasive Non-Surgical Periodontal Therapy' on July 03.

Brief Summary: This randomized controlled clinical study evaluated whether concentrated platelet-rich fibrin (C-PRF) provides additional clinical and radiographic benefits when used together with minimally invasive non-surgical periodontal treatment (MINST) in patients with advanced periodontitis and intrabony periodontal defects.

Thirty systemically healthy patients with stage III-IV periodontitis were included. Each participant had at least one intrabony defect with a probing pocket depth of 6 mm or greater and a radiographic intrabony component of 3 mm o...