U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07847242) titled 'Brain Connectivity and Inflammatory Markers During Short-Term Psychotherapy for Treatment-Resistant Depression' on Sept. 22.
Brief Summary: Some adults continue to experience depression despite treatment with antidepressant medicines. This study aimed to explore relationships between depression symptoms, brain function, and blood markers of inflammation, and changes in these measures during a course of psychotherapy.
Adults with treatment-resistant depression were assigned to receive 10 weekly sessions of individual short-term dynamic psychotherapy, a form of talking therapy, alongside their ongoing medication. Healthy adults serv...