Clinical Trial: Botensilimab, Balstilimab, and SBRT in Colorectal Cancer

U.S., Aug. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07128355) titled 'Botensilimab, Balstilimab, and SBRT in Colorectal Cancer' on Aug. 13.

Brief Summary: This is a single-arm pilot feasibility study evaluating the combination of Botensilimab and Balstilimab with Radiation Therapy (RT) in Non-Microsatellite Instability High (MSI-H) or Proficient Mismatch Repair (pMMR) chemorefractory colorectal cancer (CRC) with liver metastasis.

Study Start Date: Jan., 2026

Study Type: INTERVENTIONAL

Condition: Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis

Intervention: RADIATION: Stereotactic Body Radiation Therapy (SBRT)

Starting on Day 1 participants will have 2-4 treatments per week for about 2...