Clinical Trial: Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07852806) titled 'Bone Marrow Mononuclear Cells for the Repair of Severe Maxillofacial Bone Defects' on Sept. 07.

Brief Summary: This is a single-center, single-arm, open-label clinical study conducted at the Department of Stomatology, Nanjing Drum Tower Hospital. The study aims to evaluate the safety and efficacy of autologous bone marrow-derived mononuclear cells (BMMNCs) combined with a bone graft material (Bio-Oss) for the repair of severe maxillofacial (alveolar/jaw) bone defects caused by inflammation, trauma, or other reasons.

Approximately 20 patients aged 18-60 years with severe alveolar bone resorption requiring bone grafting will be enroll...