U.S., July 9 -- ClinicalTrials.gov registry received information related to the study (NCT07689071) titled 'Bio-Descaling Toothpaste for Dental Calculus Reduction' on June 26.
Brief Summary: Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer. It provides a substrate for bacterial colonization and soft biofilm retention, promoting the growth of pathogenic plaque, further calculus formation, gingival tissue inflammation, that could progress to periodontitis and tooth loss. Therefore, removal of dental calculus and prevention of its formation are important for maintaining periodontal health.
Professional mechanical removal remains the most effect...