U.S., Jan. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07366047) titled 'Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer' on Jan. 18.
Brief Summary: Rectal cancer patients who received low anterior resection combined with ileostomy may effectively reduce the probability of anastomotic leakage after surgery. However, due to the long-term semi-abandoned state of the distal colon, the probability of bowel dysfunction after ileostomy closure is very high. The incidence of low anterior resection syndrome (LARS) exceeds 70%, which is twice that of those who did not receive a preventive stoma. The main reasons include postoperative anatomical structure alteration, ...