U.S., May 29 -- ClinicalTrials.gov registry received information related to the study (NCT07610876) titled 'Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration' on May 20.

Brief Summary: This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar region. Sixteen patients requiring extraction and immediate implant placement will be randomly allocated into two groups. Clinical and radiographic outcomes including implant stability, peri-implant probing depth, modified bleeding index, marginal bone loss, buccal bone thickness, and ...