Clinical Trial: Association of Prosthesis Types for Aortic or Mitral Valve Replacement With Long-term Risk of Mental Disorders

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07489313) titled 'Association of Prosthesis Types for Aortic or Mitral Valve Replacement With Long-term Risk of Mental Disorders' on March 19.

Brief Summary: We identified patients aged 60 to 70 years who underwent surgical aortic or mitral valve replacement between January 1, 2013 and December 31, 2023 using procedure codes recorded in inpatient claims (N=5,528). The age range was restricted to 60 to 70 years to ensure comparability in surgical indications between prosthesis types. The exposure of interest was the type of prosthetic valve implanted at the index surgery. Mechanical prostheses were identified using procedure codes G200, G202, and G20...