U.S., Jan. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07331298) titled 'Apparent Diffusion Coefficient of the Intervertebral Disc in Children: Pilot Study' on Feb. 25, 2025.
Brief Summary: The pathophysiology of adolescent idiopathic scoliosis is unknown. This pathology develops from 10-11 years of age and progresses until skeletal maturity, or even adulthood for the most severe forms.
Current knowledge is limited as to its origin on the one hand and the evolutionary nature of scoliosis on the other.
The mechanical parameters of the intervertebral disc are incompletely known from the deep location of this organ, its fragile nature in vivo and its susceptibility to desiccation during ex-vivo analysis....