U.S., Feb. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07440069) titled 'Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor' on Feb. 17.
Brief Summary: This randomized, double-blind, placebo-controlled trial aims to compare the analgesic efficacy and obstetric effects of tramadol (100 mg IV) versus paracetamol (1 g IV) versus placebo (saline solution) in nulliparous women during active labor. The primary outcome is duration of active labor (minutes). Secondary outcomes include duration of expulsive phase, type of delivery, need for oxytocin augmentation, maternal adverse events (nausea, vomiting, somnolence, hypotension), and neonatal outcomes (Apgar scores at 1...