U.S., Feb. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07427459) titled 'Amygdala Insula Retraining in the Management of Perimenopause Symptoms' on Feb. 16.

Brief Summary: The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms.

Our research questions include:

Does AIR reduce overall perimenopausal symptom burden compared to a wait-list control?

Does AIR improve sleep disturbance, vasomotor symptom interference, fatigue, mood, anxiety, and quality of life in perimenopausal individuals?

Are symptom changes associated with improvements in autonomic regu...