U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07132814) titled 'Abuse Liability for Five Modern Oral Nicotine Products' on Aug. 13.
Brief Summary: This is a two-site, open-label, randomized, 4-way (2 arm) cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics [PD]) and plasma nicotine uptake (pharmacokinetics [PK]) during and following ad libitum use of the study investigational products (IPs) by generally healthy smokers
Study Start Date: Nov. 15, 2025
Study Type: INTERVENTIONAL
Condition:
Smoking
Smoking Behaviors
Tobacco Use
Tobacco Smoking
Intervention:
OTHER: Product A
Usual Brand (UB) filtered,...