U.S., July 14 -- ClinicalTrials.gov registry received information related to the study (NCT07699328) titled 'A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer' on July 01.
Brief Summary: This first-in-human, Phase 1/2, multicenter, open-label, non-randomized study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of VRN110755, a highly selective oral epidermal growth factor receptor (EGFR) inhibitor, in patients with EGFR-mutant non-small cell lung cancer (NSCLC).
The study includes a Phase 1a dose-escalation portion, a Phase 1b dose-expansion portion, and a Phase 2 evaluation. The study is designed to determine the maximum tolerated dose and recommended Phase 2 dose ...