Clinical Trial: A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)

U.S., Jan. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07331272) titled 'A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)' on Dec. 15, 2025.

Brief Summary: This is a prospective, single-arm, open-label and dose-escalation investigator initialed study to evaluate LUCAR-G79D in adult subjects with r/r SLE and r/r IIM.

Study Start Date: Jan. 08

Study Type: INTERVENTIONAL

Condition: Systemic Lupus Erythematosus (SLE) Idiopathic Inflammatory Myopathies(IIM)

Intervention: BIOLOGICAL: LUCAR-G79D T cells

Prior to infusion of the LUCAR-G79D T cells, subjects will receive a conditioning premedication regimen co...