Clinical Trial: A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults

U.S., Oct. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07220772) titled 'A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults' on Oct. 22.

Brief Summary: This study is researching an experimental drug called mibavademab. The study is focused on patients with a condition called monogenic obesity. Monogenic obesity is caused by a change in the leptin gene that keeps it from working properly. This causes the body to not be able to feel full or control feelings of hunger.

The aim of the study is to see how well mibavademab controls the body weight and how safe it is.

The study is looking at several other research questions, including:

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