Clinical Trial: A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer

U.S., April 15 -- ClinicalTrials.gov registry received information related to the study (NCT07527026) titled 'A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer' on April 08.

Brief Summary: In pMMR/MSS locally advanced rectal cancer, can the innovative "chemo-immunotherapy induction + LCRT + chemo-immunotherapy consolidation" approach significantly improve the complete response rate and create opportunities for organ preservation?

Study Start Date: Feb. 01

Study Type: INTERVENTIONAL

Condition: Locally Advanced Rectal Cancer

Intervention: DRUG: Camrelizumab

patients first receive 2 cycles of camrelizumab combined...