Clinical Trial: A Randomized Phase II Study of Doxorubicin With or Without DT-7012 in Advanced Soft Tissue Sarcoma

U.S., Sept. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07802652) titled 'A Randomized Phase II Study of Doxorubicin With or Without DT-7012 in Advanced Soft Tissue Sarcoma' on Aug. 31.

Brief Summary: The primary objective of this randomized phase II trial is to assess, independently in advanced/metastatic UPS and DDLPS, the antitumor activity of DT-7012 combined with doxorubicin as first-line systemic therapy.

Study Start Date: Feb. 01, 2027

Study Type: INTERVENTIONAL

Condition: Undifferentiated Pleomorphic Sarcoma (UPS) Dedifferentiated Liposarcoma (DDLPS)

Intervention: DRUG: DT-7012

DT-7012 administered IV at 10 mg/kg on Day 1 of each 21-day cycle for a total maximum of 24 months

DRUG: Doxorubi...