Clinical Trial: A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity

U.S., July 28 -- ClinicalTrials.gov registry received information related to the study (NCT07728383) titled 'A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity' on April 17.

Brief Summary: This study investigates the Topical-Lingual (T-L) delivery of semaglutide, a GLP-1 receptor agonist (GLP-1RA), via an oral liquid emulsion formulation as a Proof-of-Concept for the T-L delivery of metabolic hormones in general. GLP-1 is a gut-derived hormone that induces satiation through hypothalamic pathways.

Study Start Date: June 17

Study Type: INTERVENTIONAL

Condition: Obesity & Overweight

Intervention: DRUG: Semaglutide 6 mg liquid emulsion formulation

Semaglutide 6 mg liquid emulsion formulation daily

D...