Clinical Trial: A Longitudinal Natural History Study of OPA1-Associated Autosomal-Dominant Optic Atrophy

U.S., July 29 -- ClinicalTrials.gov registry received information related to the study (NCT07729982) titled 'A Longitudinal Natural History Study of OPA1-Associated Autosomal-Dominant Optic Atrophy' on June 21.

Brief Summary: This prospective, monocenter, non-interventional observational study investigates the natural history as well as the clinical and genetic spectrum of OPA1-associated autosomal dominant optic atrophy. Participants will undergo standardized ophthalmic and functional assessments, including visual acuity testing, visual field testing, color vision and contrast sensitivity testing, optical coherence tomography, retinal flavoprotein fluorescence imaging, and video-oculography-based ocular motor and pupillary measurements. T...