Clinical Trial: A Drug-Drug Interaction Study Between NTQ5082 Capsules and Midazolam Oral Solutio

U.S., Aug. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07745439) titled 'A Drug-Drug Interaction Study Between NTQ5082 Capsules and Midazolam Oral Solutio' on July 29.

Brief Summary: This is a single-center, non-randomized, open-label, single-sequence, self-controlled drug-drug interaction study in healthy participants.

The main purpose of the study is to evaluate whether a single dose and repeated daily doses of NTQ5082 capsules affect the pharmacokinetics of midazolam oral solution. Midazolam is used in this study as a probe drug to assess the activity of cytochrome P450 3A (CYP3A), an enzyme involved in the metabolism of many medicines.

Approximately 18 healthy male and female participants will be en...